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Depression and sexual dysfunction in chronic kidney disease: a narrative review of the evidence in areas of significant unmet need
Authors:Mariacristina Vecchio  Suetonia C Palmer  Marcello Tonelli  David W Johnson  Giovanni F M Strippoli
Institution:Correspondence and offprint requests to: Giovanni F.M. Strippoli; E-mail: strippoli@negrisud.it.
Abstract:People with chronic kidney disease (CKD) have a high symptom burden and experience poorer quality of life than the general population. People with CKD frequently report fatigue, anorexia, pain, sleep disturbance, itching and restless legs. Depression and sexual dysfunction may also be common in CKD, although questions about optimal diagnosis and treatment remain unanswered. People with kidney disease identify lifestyle and the impact of CKD on family and psychosocial supports as key priorities and rate symptoms such as sexual dysfunction and psychological distress as severe. Here, we outline the current state of research underlying depression and sexual dysfunction in this population focusing on prevalence, diagnosis, screening, outcomes and interventions and suggest areas requiring additional specific research.
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