58例细支气管肺泡癌患者手术治疗结果分析

背景与目的细支气管肺泡癌是一种特殊类型的肺癌,其发病率近年来明显上升。本研究的目的是总结分析细支气管肺泡癌的临床特点、手术方法和预后。方法回顾性分析1993年～2000年间58例有完整随访资料的细支气管肺泡癌手术病例,总结其发病特点、手术方式、肿瘤发生部位、肿瘤复发部位、预后以及术后化疗与预后的关系。结果本组51例(87.9%)行肺叶切除术。1年生存率为91.4%,3年生存率为75.9%,5年生存率为60.3%。经logrank检验,术后化疗组与术后未化疗组生存率无显著性差异(P=0.22)。结论肺叶切除术是治疗细支气管肺泡癌最常用的手术方法。细支气管肺泡癌术后化疗与否与生存率未见明显关系。

Clinical analysis of 58 surgically treated patients with bronchioloalveolar carcinoma

Background and objective Bronchioloalveolar carcinoma is a kind of special lung cancer. The aim of this study is to analyze its characteristics, surgical intervention and prognosis. Methods Fifty-eight surgically treated patients with bronchioloalveolar carcinoma from 1993 to 2000 were followed up. The clinical characteristics, surgical mode, site of recurrent disease and survival were analyzed. Results Out of 58 patients, 15 were male (25.9%), and 43 were female (74.1%). Fifty-one patients performed lobectomy ( 87.9%). The 1-, 3- and 5-year survival rate was 91.4%, 75.9% and 60.3% respectively. There was no remarkable difference in survival between chemotherapy group and non-chemotherapy group after surgery (P= 0.22). Conclusion Lobectomy is performed commonly in patients with bronchioloalveolar carcinoma. No obvious correlation is found between postoperative chemotherapy and survival.