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2型糖尿病患者颈动脉内膜中层厚度与细胞间黏附分子1、C反应蛋白的相关性
引用本文:卢曙芳,沈建国,朱麒钱,官莉莉. 2型糖尿病患者颈动脉内膜中层厚度与细胞间黏附分子1、C反应蛋白的相关性[J]. 中华内分泌代谢杂志, 2006, 22(4): 358-359
作者姓名:卢曙芳  沈建国  朱麒钱  官莉莉
作者单位:1. 绍兴文理学院附属第一医院
2. 310003,杭州,浙江大学医学院附属第一医院内分泌科
3. 绍兴市第一医院
基金项目:本课题受浙江省教育厅科研基金资助(2005-1068)
摘    要:对55例2型糖尿病(DM)患者、25名正常对照者,分别用ELISA法、免疫散射比浊法测定血清可溶性细胞间黏附分子1(sICAM-1)、超敏C反应蛋白(hs—CRP)水平,用超声测定颈动脉内膜中层厚度(IMT)。结果提示sICAM-1、hs—CRP可能与2型DM患者颈动脉IMT的增厚有关。

关 键 词:2型糖尿病 内膜中层厚度 细胞间黏附分子1 C反应蛋白
收稿时间:2005-07-18
修稿时间:2005-07-18

Association of intima-media thickness of common carotid artery with intercellular adhesion molecule-1 and C-reactive protein in type 2 diabetic patients
LU Shu-fang,SHEN Jian-guo,ZHU Qi-qian,GUAN Li-li. Association of intima-media thickness of common carotid artery with intercellular adhesion molecule-1 and C-reactive protein in type 2 diabetic patients[J]. Chinese Journal of Endocrinology and Metabolism, 2006, 22(4): 358-359
Authors:LU Shu-fang  SHEN Jian-guo  ZHU Qi-qian  GUAN Li-li
Affiliation:Department of Endocrinology, The First Hospital Affiliated to College of Medicine, Zhejiang University, Hangzhou 310003
Abstract:The intima-media thickness (IMT) of common carotid artery was measured using B-mode ultrasonography in 55 patients with type 2 diabetes mellitus (DM) and 25 normal controls. The serum levels of soluble intercellular adhesion molecule-1 ( sICAM-1) and high-sensitivity C-reactive protein ( hs-CRP) were measured by ELISA and high-sensitivity particle enhanced immunonephelometry respectively. The results suggest that sICAM-1 and hs-CRP were risk factors of thickened IMT in type 2 DM.
Keywords:Diabetes mellitus, type 2   Intima-media thickness   Intercellular adhesion molecule-l   C- reactive protein
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