小儿肝母细胞瘤4例报告及文献复习

目的探讨小儿肝母细胞瘤的临床特点和诊治方法。方法对诊治的4例小儿肝母细胞瘤的临床资料进行回顾性分析和随访。结果1例行肿瘤根治性切除加化疗,至今已无瘤生存5年5个月。3例放弃治疗,其中2例确诊半年后死亡,另1例带瘤生存已逾6个月。结论肿瘤迅速生长是肝母细胞瘤的临床特征。AFP是肝母细胞瘤的重要标志物。介入治疗、根治性肿瘤切除配合化疗是小儿肝母细胞瘤可靠而有效的治疗方法。

Hepatoblastoma in children: four cases report and clinical review of literatures

Obieetive To investigate clinical features and treatment of children with hepatoblastoma. Methods The clinical records of 4 hospitalized children diagnosed with hepatohlastoma were retrospectively analyzed and followed - up. Results One of the patients received radical resection in combination with chemotherapy have been living with tumor free for 5 years and 5 months. Three cases refused treatment and two died 6 months after diagnosis, another one has survived with tumor over six months. Conclusion The clinical feature of hepatoblastoma was that the tumor grew rapidly. AFP was an important marker of hepatobtastoma. Conclusion of intervention, radical resection and chemotherapy is the reliable and effective therapy for children with hepatoblastoma.