| 牛齿根解热、镇静、抗惊厥作用研究 |
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| 引用本文： | 苏燕生,王汝娟,郭淑民,王兴传. 牛齿根解热、镇静、抗惊厥作用研究[J]. 山东中医药大学学报, 1990, 0(3) |
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| 作者姓名： | 苏燕生 王汝娟 郭淑民 王兴传 |
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| 作者单位： | 山东中医学院药理教研室，山东中医学院无机化学教研室，山东中医学院无机化学教研室，山东中医学院无机化学教研室 |
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| 摘 要： | 新鲜老黄牛颚牙根制配成0.2g/ml 混悬剂,家兔以伤寒三联菌苗致热,体温升高1℃时分别以混悬剂、柴胡液及助悬剂灌胃,150min 牛齿根组兔温39.2±0.5,柴胡组38.5±0.4,对照组39.9±0.4。牛齿根灌胃,抖笼实验及滚棒实验,小鼠活动减少,反应迟钝,协调运动差;能延长戊巴比妥钠致小鼠的睡眠(牛齿根组108±5.1sec,对照组96.2±3.6sec),对抗戊四氮的致惊厥作用。认为动物实验符合临床牛齿根治疗小儿热病惊厥作用,机制值得进一步探讨。
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| 关 键 词： | 牛齿根 解热 镇静 抗惊厥 兔 |
RESEARCH ON PHARMACOLOGY OF MOLAR ROOT OF OX |
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| Su Yansheng Wang Rujuan Guo Shumin. RESEARCH ON PHARMACOLOGY OF MOLAR ROOT OF OX[J]. Journal of Shandong University of Traditional Chinese Medicine, 1990, 0(3) |
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| Authors: | Su Yansheng Wang Rujuan Guo Shumin |
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| Abstract: | Giving preparation of 0.2g/ml coagulant of molar root of ox to rabbits with typhoid vaccine fever,controlled by radix bupl(?)uri solvent and coa- gulant aid.150 min later temparature oi rabbits were 39.2±0.59 38.5±0.4, 39.9±0.4.Pouring the preparation to mice,hypoactivity,poor coordination of action,dullness were found.The preparation prolonged sleep state of mice taken phenobarbital(molar group 108.3±5.1 sec,controlled group 96.2±3.6 sec)and anticonvulsion of mice taken strychnine.The authers consider that the results tallied with the allaying fever and anticcnvulsion,in children. |
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| Keywords: | Molar root of ox Allaying fever Anticonvulsion Rabbit Mice |
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