Monoterpene glycoside and flavonoids from <Emphasis Type="Italic">Blumea lacera</Emphasis> |
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| Authors: | Consolacion Y Ragasa Jeannie Wong John A Rideout |
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| Institution: | (1) Chemistry Department and Center for Natural Sciences and Ecological Research, De La Salle University, 2401 Taft Avenue, Manila, 1004, Philippines;(2) Chemistry Department, De La Salle University, 2401 Taft Avenue, Manila, 1004, Philippines;(3) School of Chemical and Biomedical Sciences, Central Queensland University, Queensland, QLD, 4701, Australia |
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| Abstract: | The dichloromethane extract of air-dried leaves of Blumea lacera (Asteraceae) afforded α-pinene-7β-O-β-d-2,6-diacetylglucopyranoside (1), 5,4′-dihydroxy-6,7,3′-trimethoxyflavone (2), and 3,5,4′-trihydroxy-6,7,3′-trimethoxyflavone (3). Compounds 1–3 showed moderate activity against Candida albicans, low activity against Trichophyton mentagrophytes, and were inactive against Aspergillus niger. Compounds 1 and 3 indicated low activity against Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus and were inactive against Bacillus subtilis, while 2 was inactive against all four bacteria tested. |
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| Keywords: | Blumea lacera Asteraceae Monoterpene glycoside Flavonoids Antimicrobial |
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