牙周炎患者牙周袋内硫化物水平与牙周临床指标的相关分析

目的评价牙周炎患者牙周袋内硫化物（pS）与口气挥发性硫化物（VSC）及牙周临床指标的相关性。方法全口洁治后1周，对20例慢性牙周炎伴口臭的患者龈下刮治和根面平整（SRP）前后用Halimeter检测口气中VSC，用金刚探针检测pS，并对牙周袋内pS及菌斑指数、出血指数、探诊深度、临床附着水平纵向观察6个月。结果口内pS〉0的位点数（r=0．592，P〈0．001）和ps值（r=0．506，P〈0．001）与口气VSC均呈显著正相关；治疗后6周、3个月、6个月，pS与出血指数呈低度相关，r值分别为0．183、0．411、0．350（P〈0．05）；SRP后6周，pS及各临床指标较基线水平显著改善（P〈0．001），并在第3、6个月时进一步改善或保持稳定。结论pS值可以特异性地反映牙周袋内硫化物的水平，可作为牙周疗效判断的客观指标，反映和监测维护期的牙周组织炎症状况。

Correlations between sulfide levels in periodontal pocket of periodontitis patients and periodontal clinical parameters

OBJECTIVE: To assess the correlation between sulfide levels in periodontal and volatile sulfide compounds (VSC) in oral cavity and to assess the correlation between sulfide levels in periodontal pocket (pS) and periodontal clinical parameters. METHODS: VSC in oral cavity was measured by halimeter one week after grossly supragingival cleaning. Then pS in periodontal pockets was measured by Diamond probe/Perio 2000 system, followed by probing using Williams periodontal probe to get the records of probing depth (PD). Based on the above examination results, 4 - 8 sites with PD > or = 5 mm and/or pS > 0 were selected for the following longitude observation in each patient. The plaque index (PLI), bleeding index (BI), clinical attachment level (CAL) of the target site were recorded. The same examination was repeated during the recalling time of 6 weeks, 3 and 6 months after the initial periodontal therapy. RESULTS: VSC levels are significantly correlated with the numbers of sites with pS > 0 (r = 0.592, P < 0.001) and pS value. pS values were positively correlated with BI at low level during the maintenance time of 6 weeks, 3 and 6 months (r = 0.183, 0.411, 0.350, P < 0.05) respectively. After the initial therapy pS, PD, CAL, BI, PLI and VSC in oral cavity significantly improved at 6 weeks (P < 0.001) and further improved and kept stable at 3 and 6 months. CONCLUSIONS: pS reflects the sulfide levels in pockets with site specificity and may be considered as objective parameter to evaluate the treatment effect, and to indicate the early inflammation in periodontal tissue during the maintenance period.