百草枯中毒

百草枯（paraquat,PQ）属联吡啶类除草剂,口服中毒是中毒的主要途径,PQ中毒病死率极高.目前PQ中毒机制尚不完全清楚,多认为PQ吸收后,产生大量的氧自由基引起组织器官细胞膜脂质过氧化,造成多器官功能障碍,其中以肺损伤最常见且最严重,常导致肺水肿及肺纤维化.PQ中毒尚无特效解毒剂,治疗包括尽早洗胃、导泻、血液净化、免疫抑制及抗氧化等综合治疗.

Paraquat poisoning

Paraquat is one kind of phytocide 2,2＇-bipyridine. Oral administration is the most common way to be poisoned,and the mortality is high. As so far the mechanism of poison is not clear. It was believed that a lot of oxygen radical caused cell membrane lipid peroxidize, which lead to multiorgan disturbed. The most common and severe injury of lungs is pneumonedema and pulmonary fibrosis. There is no any antidote to paraquat poison. Treatment of paraquat poisoning is stomach washing, catharsis, blood purified, immune suppressed and antioxidation.