| 犬的体外循环模型建立和管理 |
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| 引用本文： | 赵赟,胡克俭,程玥,杨改生,张德林. 犬的体外循环模型建立和管理[J]. 中国体外循环杂志, 2004, 2(4): 217-218 |
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| 作者姓名： | 赵赟 胡克俭 程玥 杨改生 张德林 |
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| 作者单位： | 复旦大学附属中山医院心外科,上海,200032 |
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| 摘 要： | 目的 总结22条犬的体外循环实验模型建立和管理的经验。方法 健康杂种家犬22条，雄性12条，雌性10条。建立中低温阻断停跳和常温不阻断不停跳的体外循环模型。并于体外循环开始前及转流中，进行激活全血凝固时间(ACT)、血细胞压积(Hct)和血气监测。结果 转流过程中Het、PaO2、PaCO2和BE均在正常范围。结论 建立一个正确的体外循环模型是该动物实验成功的必要因素。
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| 关 键 词： | 体外循环 转流 PaO2 血细胞压积 正常范围 血气监测 PaCO2 不停跳 全血凝固时间 动物实验 |
| 文章编号： | 1672-1403(2004)04-0217-02 |
| 修稿时间： | 2004-06-25 |
The Establishment and Management of a Dog Model used for Cardiopulmonary Bypass |
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| ZHAO Yun,HU Ke-jian,CHENG Yue,YANG Gai-sheng,ZHANG De-lin. The Establishment and Management of a Dog Model used for Cardiopulmonary Bypass[J]. Chinese Journal of Extracorporeal Circulation, 2004, 2(4): 217-218 |
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| Authors: | ZHAO Yun HU Ke-jian CHENG Yue YANG Gai-sheng ZHANG De-lin |
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| Abstract: | OBJECTIVE To summary the establishment and management of 22 dogs using two model for cardiopulmonary bypass(CPB). METHODS 22 dogs (12 male , 10 female) were subject to two perfusion management models: moderate hypothermia and heart arrest & normothermia and beating heart. ACT, Hct and blood gas were measured continuously. RESULTS All results of determination were in normal range. CONCLUSION The use of the correct animal model is essential for successful dog experiments. |
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| Keywords: | Dog cardiopulmonary bypass animal model |
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