| 血小板衍生生长因子-BB在口腔种植中的应用研究进展 |
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| 引用本文： | 陈灵,徐普.血小板衍生生长因子-BB在口腔种植中的应用研究进展[J].海南医学,2014(19):2885-2887. |
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| 作者姓名： | 陈灵 徐普 |
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| 作者单位： | 中南大学湘雅医学院附属海口医院海南省口腔医学中心口腔种植科,海南 海口,570208 |
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| 摘 要： | 血小板衍生生长因子-BB（Platelet-derived growth factor,PDGF-BB）是PDGF的一个亚型,是广泛存在于多种组织的多肽生长因子,可以通过促进成骨细胞的增殖和分化及抑制破骨细胞增殖和分化的双重作用,促进口腔种植过程中骨组织的再生,同时还能促进软组织的再生。本文就血小板衍生生长因子-BB修复组织缺损的作用作一综述。
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| 关 键 词： | 血小板衍生生长因子-BB 口腔种植 软硬组织 组织再生 |
Application of platelet-derived growth factor-BB in oral implant |
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| CHEN Ling,XU Pu.Application of platelet-derived growth factor-BB in oral implant[J].Hainan Medical Journal,2014(19):2885-2887. |
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| Authors: | CHEN Ling XU Pu |
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| Institution: | ( Oral Implant Department of Stomatology Center, Affiliate Haikou Hospital of Xiangya Medical school, Central South University, Hainan Provincial Stomatology Center, Haikou 570208, Hainan, CHINA) |
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| Abstract: | Objective Platelet-derived growth factor-BB（PDGF-BB）, a subtype of PDGF, is a polypeptide growth factors which widely exists in multiple tissues. PDGF-BB playes a dual role in promoting osteoblast proliferation and differentiation and inhibiting osteoclast proliferation and differentiation, and consequently helps the regeneration of bone tissue in the process of oral planting. Meanwhile, it could also promote the regeneration of the soft tissue.The effects of PDGF-BB in tissue reparation are summarized in this review. |
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| Keywords: | Platelet-derived growth factor-BB Dental implant Hard and soft tissue Tissue regeneration |
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