Studies on the in vivo Elution of 51Cr from Baboon Red Blood Cells1,2,3

Abstract. Four anticoagulant solutions were added to baboon red blood cells prior to labeling with ⁵¹Cr to determine how each would influence the distribution of ⁵¹Cr within the red blood cells, the loss of ⁵¹Cr from the red blood cells after transfusion, and the calculated red cell survival value. The ⁵¹Cr label was detected in the hemoglobin and in the low molecular weight compounds within the red blood cells. The elution of ⁵¹Cr from labeled baboon red blood cells following transfusion could not be explained by the distribution of ⁵¹Cr between hemoglobin and low molecular weight compounds within the red blood cells.