35例非霍奇金淋巴瘤综合治疗中放疗应用的探讨

目的探讨放射治疗在非霍奇金淋巴瘤综合治疗中的疗效及地位。方法对35例非霍奇金淋巴瘤行CHOP方案为主化疗后累及野放疗,统计及有效率及2年生存率并观察其副作用。结果化疗后再行放疗有效率为CR:91%(32/35),PR:9%(3/35),有效率100%。2年生存率88.6%(31/35)。结论非霍奇金淋巴瘤的主要治疗为放化疗,Ⅰ～Ⅱ期非霍奇金淋巴瘤多数采用化疗后行累及野放疗,Ⅲ～Ⅳ期淋巴瘤在化疗的基础上,对于未达CR的,或肿瘤侵犯重要脏器或影响生活的,可考虑行姑息性放疗,放疗剂量30～50Gy即可(患者体质及原肿块、残留肿块大小,肿瘤消退情况,剂量不同),患者对放疗耐受性较好。

The Application of Radiotherapy of 35 NHL Patients in Comprehensive Treatment is Discussed

Objective To study the effect and position of radiotherapy in non-hodgkin＇s lymphoma patients in comprehensive treatment.Method After CHOP chemotherapy,thirty-five NHL patients were treated with radiotherapy,observed the efficient rate and 2 years of survival rate and observed the side effects of chemotherapy.Results The efficient afer radiation and chemotherapy is CR： 91%（32/35）,PR： 9%（3/35）,effective rate was 100%.2 years of survival rate 88.6%（31/35）.Conclusions The main treatment of NHL patients is radiotherapy and chemotherapy,ToⅠ-Ⅱ period NHL patients,after chemotherapy,radiotherapy is necessary,To Ⅲ-Ⅳ period HNL patients,after chemotherapy,some patients can not achieve CR,or tumor invade the adjacent important organs or influence the life,radiotherapy is also necessary,30 to 50 gy（patients constitution and the original mass,residual tumor size,tumor resolve,different doses of radiation therapy,patients tolerated） is good.