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Immature ovarian teratoma with peritoneal gliomatosis and elevated serum alpha-fetoprotein associated with a second mature teratoma |
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| Authors: | A. Hokama M. Yamasato N. Tokumine B. Nakama Y. Muto T. Toda Y. Shingaki K. Hirayama |
| Affiliation: | (1) The First Department of Surgery, School of Medicine, University of the Ryukyus, 207 Uehara, 903-01 Nishihara-cho, Okinawa, Japan;(2) Department of Clinical and Laboratory Medicine, School of Medicine, University of the Ryukyus, 207 Uehara, 903-01 Nishihara-cho, Okinawa, Japan;(3) Department of Pediatrics, School of Medicine, University of the Ryukyus, 207 Uehara, 903-01 Nishihara-cho, Okinawa, Japan |
| Abstract: | A 7-year-old girl had a huge immature grade 2 teratoma of the left ovary with peritoneal gliomatosis and elevated serum alpha-fetoprotein (AFP). The serum AFP level reached 3543 ng/ml and returned to normal after left salpingo-oophorectomy and chemotherapy. Twenty-two months later, a second mature teratoma was removed from the left subdiaphragmatic region. The AFP level had been within the normal range and the patient had been symptom-free for 3 years following the previous operation. AFP was positive in the tubular epithelium of the immature tissues on immunohistochemical study.Offprint requests to: A. Hokama |
| Keywords: | Immature teratoma of the ovary Peritoneal gliomatosis Alpha-fetoprotein Mature teratoma |
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