Nuclear factor Y regulation and promoter transactivation of human ribonucleotide reductase subunit M2 gene in a Gemcitabine resistant KB clone |
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Authors: | Liu Xiyong Zhou Bingsen Xue Lijun Qiu Weihua Shih Jennifer Zheng Shu Yen Yun |
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Affiliation: | Department of Medical Oncology & Therapeutic Research, City of Hope National Medical Center, 1500 E. Duarte Road, Duarte, CA 91010-3000, USA. |
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Abstract: | |
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Keywords: | NF-Y, nuclear factor Y hRR, human ribonucleotide reductase hRRM2, human ribonucleotide reductase subunit M2 hRRM1, human ribonucleotide reductase subunit M1 p53R2, p53 dependant ribonucleotide reductase subunit R2 KBGem, Gemcitabine drug resistance KB cell clone HU, hydroxyurea Gem, 2′,2′-dFdCyd3, 2,2-difluorodeoxycytidine, Gemcitabine TSA, trichostatin A HDAC, histone deacetylases HAT, histone acetyltransferases hENT1, human equilibrative nucleoside transporter 1 DCK, deoxycytidine kinase CDA, cytidine deaminase 5′-Nucl, 5′-nucleotidase dNTP, deoxynucleoside triphosphate dCTP, deoxycytidine triphosphate |
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