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Nuclear factor Y regulation and promoter transactivation of human ribonucleotide reductase subunit M2 gene in a Gemcitabine resistant KB clone
Authors:Liu Xiyong  Zhou Bingsen  Xue Lijun  Qiu Weihua  Shih Jennifer  Zheng Shu  Yen Yun
Affiliation:Department of Medical Oncology & Therapeutic Research, City of Hope National Medical Center, 1500 E. Duarte Road, Duarte, CA 91010-3000, USA.
Abstract:
Keywords:NF-Y, nuclear factor Y   hRR, human ribonucleotide reductase   hRRM2, human ribonucleotide reductase subunit M2   hRRM1, human ribonucleotide reductase subunit M1   p53R2, p53 dependant ribonucleotide reductase subunit R2   KBGem, Gemcitabine drug resistance KB cell clone   HU, hydroxyurea   Gem, 2′,2′-dFdCyd3, 2,2-difluorodeoxycytidine, Gemcitabine   TSA, trichostatin A   HDAC, histone deacetylases   HAT, histone acetyltransferases   hENT1, human equilibrative nucleoside transporter 1   DCK, deoxycytidine kinase   CDA, cytidine deaminase   5′-Nucl, 5′-nucleotidase   dNTP, deoxynucleoside triphosphate   dCTP, deoxycytidine triphosphate
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