| 实验性糖尿病大鼠血清一氧化氮与肾功能低下的相关性研究 |
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| 引用本文： | 高雪玲,苗乃全,付秀云,陶慧然. 实验性糖尿病大鼠血清一氧化氮与肾功能低下的相关性研究[J]. 牡丹江医学院学报, 2001, 22(2): 9-11 |
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| 作者姓名： | 高雪玲 苗乃全 付秀云 陶慧然 |
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| 作者单位： | 1. 牡丹江医学院，
2. 黑龙江省宾县医院, |
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| 摘 要： | 目的：对实验性糖尿病大鼠血清一氧化氮（Nitric Oxide,NO)与肾功能低下进行相关分析。方法：采用链尿佐菌素复制糖尿病动物模型，比色测定其血清NO－一氧化氮合成酶（No synthetase,NOS)活力，肌酐（Creatinine,Cr)和尿素氮（Blood urea nitrogen,BUN)含量，结果：糖尿病组大鼠各项指标均高于正常组，随病程延长差异显著（P＜0．01），结论：糖尿病大鼠血清NO与肾功能低下呈高度正相关。
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| 关 键 词： | 实验性糖尿病 一氧化氮 肾功能低下 大鼠 |
THE STUDY ON THE CORRELATION OF SERUM NO WITH RENAL INJURY IN EXPERIMENTAL DIABETIC RATS |
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| Gao xueling et al Mudanjiang Medical college. THE STUDY ON THE CORRELATION OF SERUM NO WITH RENAL INJURY IN EXPERIMENTAL DIABETIC RATS[J]. Journal of Mudanjiang Medical College, 2001, 22(2): 9-11 |
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| Authors: | Gao xueling et al Mudanjiang Medical college |
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| Affiliation: | Gao xueling et al Mudanjiang Medical college 157011 |
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| Abstract: | Objective:To analysis the correlation of serum No.with the renal injury in experimental diabetic rats.Method:using STZ induced diabetic experimental models in rats .The indexes of serum NO.activity of NOS.Cr and BUN were measured.Results:The level of all the indexes was higher than normal group and the difference was increased with the course of disease lasting (p<0.01) Conclusion: Serum NO was positive correlated with renal injury in experimental diabetie rats. |
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| Keywords: | experimental diabetic NO renal injury |
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