多内分泌功能性嗜铬细胞瘤的临床诊治(附3例报告)

目的:探讨多内分泌功能性嗜铬细胞瘤的临床、病理、组织化学特性和诊治方法及预后。方法:回顾性分析3例多内分泌功能性嗜铬细胞瘤患者的临床资料,并结合文献复习就其诊治方法予以讨论。结果:1例行开放性右肾上腺肿瘤切除术,术后血压恢复正常,Cushing综合征表现明显减轻;1例行后腹腔镜下右肾上腺区肿物切除术,术后患者腹泻消失,定期复查血钾正常;另1例死于高血压危象。结论:多内分泌功能性嗜铬细胞瘤病因尚不明确,其中分泌促皮质激素表现为Cushing综合征者相对较多,但临床易漏诊误诊。正确的诊断思路和充分的实验室检查及术前准备是诊疗的关键;治疗方式上以后腹腔镜下或开放切除肾上腺肿瘤为主。

Multiple endocrine neoplasia pheochromocytoma(Report of 3 cases)

Objective:To investigate the clinical,pathology,histochemistry,prognosis,diagnosis and treatment of multiple endocrine neoplasia pheochromocytoma.Methods:Clinical data of 3 cases multiple endocrine neoplasia pheochromocytoma was reviewed retrospectively and the literature of recent years was navigated.Results:Two cases underwent adrenalectomy(open or laparoscopic)and recovered from hypertension,diarrhea and hypokalemic,1 case died from hypertensive crisis.Conclusions:Etiological factor of multiple endocrine neoplasia pheochromocytoma is still unclear.The right way of diagnosis,sufficient laboratory examination and preoperative preparation ensure a successful operation.Laparoscopic or open adrenalectomy is the treatment of choice.