改良根治加带蒂背阔肌皮瓣移植术治疗局部晚期乳腺癌25例体会

目的探讨乳腺癌改良根治加带蒂背阔肌皮瓣移植术在针对局部晚期乳腺癌的治疗价值。方法阳江市人民医院乳腺科2008年12月至2010年12月对25例癌肿侵犯皮肤的局部晚期乳腺癌进行新辅助化疗后,予乳腺癌改良根治加带蒂背阔肌皮瓣移植术治疗。结果所有的病例治疗后随访1年,25例患者手术无1例出现严重并发症,患者生活质量佳,21例复查乳腺彩超、腹部B超、胸片、全身骨扫描等检查,未发现局部和淋巴结复发及远处转移,2例出现骨转移,1例出现腋窝复发,1例肺转移后死亡。结论乳腺癌改良根治加带蒂背阔肌皮瓣移植术针对部分癌肿侵犯皮肤的局部晚期乳腺癌有较重大的临床应用。

Experience of the treatment for locally advanced breast cancer in 25 cases by modified radical mastectomy with pedicled latissimus dorsi muscle flap transplantation

Objective To explore value of the treatment of modified radical mastectomy for breast cancer with pedicled latissimus dorsi muscle flap transplantation for locally advanced breast cancer.Methods From December 2008 to December 2010,25 patients of locally advanced breast cancer with skin involvement was treated by modified radical with pedicled latissimus dorsi muscle flap transplantation,after neoadjuvant chemotherapy.Results All the cases were followed up for 1 year,21 cases were found with no local recurrence and distant metastasis and good on quality of life,2 cases were found with bone metastasis,1 cases were found with axillary recurrence,1 cases was dead after pulmonary metastasisbone.Conclusion Modified radical mastectomy for breast cancer with pedicled latissimus dorsi muscle flap transplantation have a significant clinical application on the treatment to locally advanced breast cancer with skin involvement.