氯氮平、舒必利及氯氮平合并舒必利治疗精神分裂症阴性症状的对照分析

作者对93例以阴性症状为主要临床相的精神分裂症患者分别应用氯氮平、舒必利及氯氮平合并舒必利治疗，并就其疗效与治疗前后SANS量表分进行分析。结果发现，三者疗效相近，治疗后SANS虽表分氯氮平组与舒必利组无明显差异，合并用药组治疗后SANS量表分明显低于氯氮平组和舒必利组，特别是情感平淡、思维贫乏两个症状分改善明显。

CONTRAST ANALYSIS ON NEGATIVE SYMPTOM OF SCHIZOPHRENIA BY CLOZAPINE、SULP─IRIDE AND THEIR COMBINATION

93 cases with schizophrenia, its major clinical indication being negative symptom were treated by Clozapine, Sulpirideand their combination. The curative effect and the SANS content table of the pretreatment and posttreatment were analysed. The results showed that the curative effects of the three were similar. The SANS contents table after the treatment in Clozapine group and Sulpiride group had no evident difference and that in the combination was lower than in Clozapine group and Sulpiride group, especially the two symptoms of apathia and lack of thought had markedly improved.