Detection of lymph-node metastases in patients with gastric carcinoma: comparison of three MR imaging pulse sequences |
| |
Authors: | M Kato S Saji M Kanematsu D Fukada K Miya T Umemoto K Kunieda Y Sugiyama H Takao Y Kawaguchi Y Takagi H Kondo H Hoshi |
| |
Institution: | (1) Second Department of Surgery, Gifu University School of Medicine, 40 Tsukasamachi, Gifu 500-8705, Japan, JP;(2) Department of Radiology, Gifu University School of Medicine, 40 Tsukasamachi, Gifu 500-8705, Japan, JP |
| |
Abstract: | Background: To compare the diagnostic accuracy of magnetic resonance (MR) images obtained with three different pulse sequences for lymph-node
metastases in patients with gastric cancer.
Methods: T1-weighted spin-echo (SE), breath-hold T2-weighted fast SE, and triphasic gadolinium-enhanced dynamic gradient-recall-echo
(GRE) MR images obtained in 16 patients with gastric carcinoma were retrospectively reviewed. Regional lymph nodes were assigned
to four different groups, and image review was conducted on a lymph-node group-by-group basis; 64 lymph-node groups were reviewed
by two radiologists. Relative sensitivity, specificity, and accuracy were determined based on the findings with definitive
surgery and follow-up imaging. Diagnostic accuracy was determined by means of receiver-operating-characteristic (ROC) analysis.
Results: Relative sensitivities for lymph-node metastases with T1-weighted SE, breath-hold T2-weighted fast SE, and dynamic GRE images
were 61%, 94%, and 59%, respectively. Relative sensitivity with breath-hold T2-weighted fast SE images was significantly greater
than that with T1-weighted SE (p < 0.05) and dynamic GRE (p < 0.05) images. Diagnostic accuracy determined by ROC analysis was marginally higher with breath-hold T2-weighted fast SE (area under
ROC curve Az]= 0.87) than with T1-weighted SE (Az = 0.78, p= 0.08) and dynamic GRE (Az = 0.79, p= 0.12) images.
Conclusion: Breath-hold T2-weighted fast SE sequence is useful in the detection of regional lymph-node metastases in patients with gastric
carcinoma.
Received: 11 November 1998/Revision accepted: 7 April 1999 |
| |
Keywords: | : Gastric carcinoma— Lymph node— Magnetic resonance— Pulse sequence— Receiver-characteristic-curve analysis |
本文献已被 PubMed SpringerLink 等数据库收录! |
|