| 肠道菌群与肥胖关系的研究进展 |
| |
| 引用本文： | 黄晓飞,陆颖理.肠道菌群与肥胖关系的研究进展[J].医学综述,2014(1):82-84. |
| |
| 作者姓名： | 黄晓飞 陆颖理 |
| |
| 作者单位： | [1]上海交通大学医学院,上海200025 [2]上海交通大学医学院附属第九人民医院内分泌科,上海200011 |
| |
| 摘 要： | 肥胖现已成为困扰世界各国的公共卫生问题之一,其发生、发展是遗传背景和环境因素综合作用的结果。近来越来越多的证据表明,作为人体肠道生态系统的重要组成部分,肠道菌群与肥胖的发生、发展有着密切关系。肠道菌群改变能量摄取、引发慢性系统炎症、影响肠道激素分泌、激活内源性大麻素系统等作用的发现,为肥胖的治疗提供了新的线索。
|
| 关 键 词： | 肠道菌群 肥胖 能量平衡 慢性系统炎症 |
Research Progress of the Relationship between Gut Microbiota and Obesity |
| |
| Institution: | HUANG Xiao-fei , LU Ying-li. ( 1. Shanghai Jiaotong University School of Medicine, Shanghai 200025, China ; 2. Department of Endocrinology,the Ninth People＇s Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai 200011, China) |
| |
| Abstract: | Obesity has become a worldwide public health problem. Its occurrence and development are generally considered as a combined effect of genetic background and environmental factors. Recently, more and more evidence shows that as an important component of human intestinal ecological system, the gut microbiota is closely related to the occurrence and development of obesity. Proposed mechanisms for the role of gut microbiota include the increase of energy harvest from the diet, causing chronic system inflammation, effects on gut-hormone production, and activation of the endocannabinoid system. These discoveries can pro- vide new clues for the treatment of obesity. |
| |
| Keywords: | Gut mierobiota Obesity Energy homeostasis Chronic systemic inflammation |
| 本文献已被 CNKI 维普 等数据库收录！ |
|
