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| 一种新的兔株网膜下腔出血后症状性脑血管痉挛模型的建立 | |
| 引用本文： | 施国君,刘俊雄,王敏.一种新的兔株网膜下腔出血后症状性脑血管痉挛模型的建立[J].中国组织工程研究与临床康复,2002,6(1):134-135. |
| 作者姓名： | 施国君 刘俊雄 王敏 |
| 作者单位： | 1. Tangdu Hospital，Fourth Military Medical University，Xi'an 710038，China;2.Shangluo Hospital，Shangluo 726000，China;3.89th Hospital of PLA，Weifang 261021，China |
| 摘 要： | Subarachnoidhemorrhagecaninducescerebralvasospasm，whichisamajorcauseofmortalityandneurologicalmorbidity．Somanymodelshavebeenestablishedtomimickhumansituation．Re－centyearshaveseenlotsofdevelopmentsintheestablishmentofCVSmodel．HerewereportoursymptomaticCVSmodelbasedonEndo＇s．１Subjectandmethod１．１SubjectWeentered２４rabbitsofeithersexweighing２．４～３．０kgintoourstudy．Inallrabbits，bothcommoncarotidarterieswereligated２weeksbeforetheplannedSAH．Allsurgicalprocedureswereperformed… |
Establishment of a new symptomatic cerebral vasospasm model following subarachnoid hemorrhage in rabbit |
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| SHI Guo jun,GAO Guo dong,LIU Jun xiong,WANG Min.Establishment of a new symptomatic cerebral vasospasm model following subarachnoid hemorrhage in rabbit[J].Journal of Clinical Rehabilitative Tissue Engineering Research,2002,6(1):134-135. | |
| Authors: | SHI Guo jun GAO Guo dong LIU Jun xiong WANG Min |
| Institution: | 1. Tangdu Hospital,Fourth Military Medical University, Xi'an 710038,China 2. Tangdu Hospital,Fourth Military Medical University, Xi'an 710038,China;Shangluo Hospital,Shangluo 726000,China 3. 89th Hospital of PLA,Weifang 261021,China |
| Abstract: | Objective To establish an experimental model of symptomatic cerebral vasospasm(CVS) after subarachnoid hemorrhage( SAH) in rabbits. Method 2 weeks after the ligation of bilateral common carotid arteries, We induced CVS by injecting arterial blood twice via a cranial hole 2 mm× 2 mm and then neurological symptoms ,cerebral blood flow(rCBF) and food intake were evaluated. Results Food intake and rCBF decreased and neurological disorders were observed. Conclusion An experimental rabbit model of symptomatic CVS can be established by injecting blood via a cranial hole after bilateral common carotid arteries ligation. `` |
| Keywords: | subarachnoid hemorrhage cerebral vasospasm cerebral blood flow neurological disorders animal modelsCLC number:R743 Document code:A Article ID:1671-5926(2002)01-00134-02 |
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