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Mutations in Exon 1 Highlight the Role of MED12 in Uterine Leiomyomas
Authors:Kati Kämpjärvi  Min Ju Park  Miika Mehine  Nam Hee Kim  Alison D. Clark  Ralf Bützow  Tom Böhling  Jan Böhm  Jukka‐Pekka Mecklin  Heikki Järvinen  Ian P.M. Tomlinson  Zephne M. van der Spuy  Jari Sjöberg  Thomas G. Boyer  Pia Vahteristo
Affiliation:1. Department of Medical Genetics, Genome‐Scale Biology Research Program, University of Helsinki, Helsinki, Finland;2. Department of Molecular Medicine, Institute of Biotechnology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA;3. Department of Pathology, The Laboratory of Helsinki University Central Hospital (HUSLAB), Helsinki University Central Hospital and Haartman Institute, University of Helsinki, Helsinki, Finland;4. Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland;5. Department of Pathology, Jyv?skyl? Central Hospital, Jyv?skyl?, Finland;6. Department of Surgery, Jyv?skyl? Central Hospital and University of Eastern Finland, Jyv?skyl?, Finland;7. Department of Surgery, Helsinki University Central Hospital, Helsinki, Finland;8. Wellcome Trust Centre for Human Genetics and NIHR Comprehensive Biomedical Research Centre, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK;9. Department of Obstetrics and Gynaecology, Faculty of Health Sciences, University of Cape Town/Groote Schuur Hospital, Cape Town, South Africa
Abstract:
Keywords:MED12  uterine leiomyoma  somatic mutation  benign tumor  cancer
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