| 新型肺部给药系统-吸入粉雾剂 |
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| 引用本文： | 汤 玥,朱家壁,陈西敬. 新型肺部给药系统-吸入粉雾剂[J]. 药学学报, 2009, 44(6): 571-574 |
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| 作者姓名： | 汤 玥 朱家壁 陈西敬 |
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| 作者单位： | (中国药科大学 1. 药物制剂研究所, 2. 药物代谢研究中心, 江苏 南京 210009) |
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| 摘 要： | 吸入粉雾剂 (又名粉雾吸入剂、干粉吸入剂、粉雾剂) 是一种新型的肺部给药系统, 具有稳定性好, 不含抛射剂氟里昂等优点, 近年来受到人们的广泛关注。粉雾剂由粉末吸入装置和供吸入用的干粉组成。本文就近年来粉雾剂的研究进展, 包括吸收机制, 粉雾剂品种, 吸入装置, 制备技术和评价特征参数等进行了综述。
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| 关 键 词： | 吸入粉雾剂 吸收 制备 |
A novel pulmonary delivery system — dry powder inhalers |
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| Abstract: | Dry powder inhalers (DPIs) have received considerable attention because of their propellant-free composition and stability. DPIs include the DPI devices and inhalation powders. The purpose of this review is to address the development of the DPIs, including the mechanisms of absorption, the products, the devices, the preparation technology, and the characteristics. |
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| Keywords: | dry powder inhaler absorption preparation |
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