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Left Ventricular Noncompaction
Authors:Radha J Sarma  Amar Chana
Institution:a ABIM, Internal Medicine and Cardiovascular Diseases, University of Southern California, Keck School of Medicine, Division of Cardiovascular Medicine, Los Angeles County + USC Medical Center, Los Angeles, CA 90033, USA
b Cardiovascular Medicine, University of Southern California, Keck School of Medicine, Los Angeles County + USC Medical Center, Los Angeles, CA 90033, USA
c University of Southern California, Keck School of Medicine, Division of Cardiovascular Medicine, Los Angeles County + USC Medical Center, Los Angeles, CA 90033, USA
Abstract:According to the World Health Organization classification of cardiomyopathies, left ventricular noncompaction is still an unclassified cardiomyopathy. In 2006, the American Heart Association classified this entity as a primary cardiomyopathy of genetic origin. In 2008, the European Society of Cardiology updated the classification scheme similar to the World Health Organization classification. At present, there is no consensus on the diagnostic criteria, and diagnosis is based on the morphologic features identified by cardiac imaging studies or at autopsy. Due to lack of standardization of the diagnostic criteria and little awareness of this condition among clinicians, the true prevalence of this disease is not clear. There is no specific therapy for this condition. However, it seems prognosis is much better than initially reported. The current status of diagnosis, prognosis, and management of isolated noncompaction in adults is discussed in this review.
Keywords:ACC  American College of Cardiology  AF  atrial fibrillation  AHA  American HeartAssociation  C  compact  CMR  cardiac magnetic resonance  CRT  cardiac resynchronizationtherapy  CT  computed tomography  ICD  implantable cardioverter-defibrillator  LV  left ventricular  LVNC  left ventricular noncompaction  NC  noncompacted  NYHA  New York Heart Association
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