Left Ventricular Noncompaction |
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Authors: | Radha J Sarma Amar Chana |
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Institution: | a ABIM, Internal Medicine and Cardiovascular Diseases, University of Southern California, Keck School of Medicine, Division of Cardiovascular Medicine, Los Angeles County + USC Medical Center, Los Angeles, CA 90033, USA b Cardiovascular Medicine, University of Southern California, Keck School of Medicine, Los Angeles County + USC Medical Center, Los Angeles, CA 90033, USA c University of Southern California, Keck School of Medicine, Division of Cardiovascular Medicine, Los Angeles County + USC Medical Center, Los Angeles, CA 90033, USA |
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Abstract: | According to the World Health Organization classification of cardiomyopathies, left ventricular noncompaction is still an unclassified cardiomyopathy. In 2006, the American Heart Association classified this entity as a primary cardiomyopathy of genetic origin. In 2008, the European Society of Cardiology updated the classification scheme similar to the World Health Organization classification. At present, there is no consensus on the diagnostic criteria, and diagnosis is based on the morphologic features identified by cardiac imaging studies or at autopsy. Due to lack of standardization of the diagnostic criteria and little awareness of this condition among clinicians, the true prevalence of this disease is not clear. There is no specific therapy for this condition. However, it seems prognosis is much better than initially reported. The current status of diagnosis, prognosis, and management of isolated noncompaction in adults is discussed in this review. |
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Keywords: | ACC American College of Cardiology AF atrial fibrillation AHA American HeartAssociation C compact CMR cardiac magnetic resonance CRT cardiac resynchronizationtherapy CT computed tomography ICD implantable cardioverter-defibrillator LV left ventricular LVNC left ventricular noncompaction NC noncompacted NYHA New York Heart Association |
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