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指纹图谱技术在中药对照物质标定中的应用
引用本文:刘燕,聂黎行,林瑞超. 指纹图谱技术在中药对照物质标定中的应用[J]. 中国药事, 2011, 25(7): 638-639
作者姓名:刘燕  聂黎行  林瑞超
作者单位:中国食品药品检定研究院,北京,100050
基金项目:科技部“十一五”科技支撑计划课题(编号2009ZX09308)
摘    要:目的探讨指纹图谱技术在中药对照物质标定中的应用。方法采用HPLC法建立了银杏叶对照药材和银杏叶对照提取物的指纹图谱测定方法。结果样品指纹图谱相似度均大于0.90。结论所建方法可全面客观地反映银杏叶对照药材和银杏叶对照提取物的化学特征,保证其质量稳定可控。

关 键 词:中药对照物质  银杏叶  银杏叶提取物  指纹图谱

Application of Fingerprinting Technology in Calibration of TCM Reference Substance
Liu Yan,Nie Lixing,Lin Riuchao. Application of Fingerprinting Technology in Calibration of TCM Reference Substance[J]. Chinese Pharmaceutical Affairs, 2011, 25(7): 638-639
Authors:Liu Yan  Nie Lixing  Lin Riuchao
Affiliation:Liu Yan,Nie Lixing and Lin Ruichao(National Institute for Food and Drug Control,Beijing 100050)
Abstract:Objective To investigate application of fingerprinting technology in calibration of TCM reference substance.Methods Fingerprints of Ginkgo Leaf reference drug and Ginkgo leaves reference extract were established by HPLC method.Results Similarities of all samples were above 0.90.Conclusion The proposed method can reflect the chemical characteristics of Ginkgo leaf reference drug and Ginkgo leaves reference extract in an objective and comprehensive way,and ensure their quality stable and controllable.
Keywords:TCM reference substance  Ginkgo leaf  Ginkgo leaves extract  fingerprint  
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