云南省独龙族6～24月龄婴幼儿贫血调查研究

目的了解云南独龙族少数民族地区6~24月龄婴幼儿贫血检出率和贫血类型,录求发生贫血的原因,并为"云南省贫困地区儿童营养改善项目"营养包的服用及制定相应的干预措施提供科学依据。方法整群抽取本地区6~24月龄婴幼儿的静脉血EDTA-K2抗凝2ml,通过sysmex-21N血细胞分析仪分析、铁蛋白(SF)的检测、法国sebia capillarys 2flex piercing毛细管仪血红蛋白电泳和美国伯乐CFX96PCR仪进行地中海贫血基因检测,对结果进行统计分析。结果本地区本群婴幼儿贫血的检出率为54.2%(65/120),以轻中度贫血为主,细胞形态以小细胞低色素为主(占比为84.2%),血清铁蛋白(SF)缺乏率57.5%,地中海贫血检出率为0%。结论独龙族6~24月婴幼儿贫血的检出率仍较高,且以缺铁性贫血为主,服用"云南省贫困地区儿童营养改善项目"营养包对改善贫血有一定的帮助。

Investigation of anemia of 6~24 months old infants among Drung ethnic minority in Yunnan province

Objective To find out the rate,type and cause of anemia of 6 to 24 months old infants from Yunnan Drung minority area,and to provide a scientific basis for nutrition package taking of "Yunnan poor areas children's nutrition improvement project" and the prevention anemia measures. Methods Using cluster samping method,the vein blood of local area 6~24 months old infants collected,and analysis was detected serum ferritin (SF) by sysmex-21N blood cell analyzer,the SEBIA capillarys 2 flex piercing hemoglobin electrophoresis analyzer was used for hemoglobin electrophoresis,the BIO-RAD CFX96 PCR was used to diagnose thalassemia gene.Finally,all data were carried on the statistical analysis. Result Local infant anemia incidence rate was 54.2% (65/120),the major anemia type was mild anemia,wich cell morphology was in cellule low pigment based (accounted for 84.2%),SF lack was 57.5%,Thalassemia was 0%. Conclusions The anemia incidence rate is more higher among 6~24 months infant of Drung minority.The major type of anemia was iron deficiency anemia,that is extraordinary important guiding for taking the nutrition package.