连续捐献单采血小板献血者血红蛋白和铁蛋白状况调查及分析

目的 调查连续捐献单采血小板对献血者血红蛋白和铁蛋白的影响.方法 选择2018年3-6月北京市红十字血液中心男性献血者73名(平均献血周期为15.26d),依据5次献血的铁蛋白水平分为第1组(n=21,≥30 μg/L)、第2组(n=23,＜30pug/L)和第3组(n=29,在30 μg/L上下变化),对其连续捐献5...

Hemoglobin and ferritin status in frequent plateletpheresis donors

Objective To investigate and analyze the effect of frequent platelet donation on hemoglobin(Hb) and ferritin in blood donors. Methods 73 male plateletpheresis donors, with an average donation interval of 15.26 days, in Beijing Red Cross Blood Center between March 2019 to June 2019 were enrolled into this study. These donors were classified into 3 groups according to the ferritin level during the 5 consecutive donations: 1st group(n=21, ferritin ≥30 μg/L), 2nd group(n=23, ferritin<30 μg/L) and 3rd group(n=29, ferritin fluctuated at 30 μg/L). Their Hb and ferritin during the 5 consecutive donation were detected and further analyzed.Results 1) No significant difference was found in Hb during the 5 consecutive donations(P>0.05), and the ferritin decreased gradually(P<0.01). The incidence of low-value ferritin increased with the donations(35.62%-63.01%). 2) The same change trend in Hb and ferritin was observed in 1st and 2nd group, except for Hb at 4th donation was significantly higher in 1st group than it in 2nd group. 3) Increasing Hb threshold for donation from 120 g/L to 135 g/L can reduce the incidence of low-value ferritin from 23.23% to 18.00%, but also lead to a decrease of blood resources by 10.61%.Conclusion A progressive decline in iron reserve was observed in frequent platepheresis donors, with minimal impact of Hb on reducing the risk of iron deficiency. It is particularly necessary to carry out ferritin testing for frequent platepheresis donors.