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Soluble receptors of TNF-alpha in rheumatoid arthritis |
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| Authors: | Nasonov E L Chichasova N V Samsonov M Iu Tilz G P Nikiforova E L Stepanets O V Nasonova M B Fuks D |
| Abstract: | The serum level of soluble TNF-alpha receptors with molecular mass 55 kDa (sTNF-a55R) was measured by enzyme immunoassay with commercial kits in 30 patients with rheumatoid arthritis (RA) and 38 healthy donors. High sTNF-a55R serum levels were registered in 90% of RA patients. These levels correlated with RA activity by DAS. Thus, assay for sTNF-a55R can be used for assessing RA activity. |
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