| 大蒜素对解脲脲原体的体外抗菌作用 |
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| 引用本文： | 闻平,郭月芳,陈蕾. 大蒜素对解脲脲原体的体外抗菌作用[J]. 中国中西医结合皮肤性病学杂志, 2006, 5(2): 99-100 |
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| 作者姓名： | 闻平 郭月芳 陈蕾 |
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| 作者单位： | 1. 镇江市第一人民医院检验科
2. 江苏大学附属医院中心实验室,镇江,212001 |
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| 摘 要： | 目的检测解脲脲原体对大蒜素及临床常用的5种抗生素的敏感性,为临床合理用药提供实验依据.方法采用微量肉汤稀释法检测了大蒜素及临床常用的5种抗生素对197株Uu的最低抑菌浓度(MIC)和最小杀菌浓度(MBC)的作用.结果大蒜素对Uu有较强的抑杀作用,MIC50和MIC90分别为2.0mg/L和4.0mg/L.结论天然药物大蒜素对Uu有较强的体外抑杀作用.
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| 关 键 词： | 解脲脲原体 大蒜素 抗生素 最低抑菌浓度(MIC) 最小杀菌浓度(MBC) 敏感性 |
| 文章编号： | 1672-0709（2006）02-0099-02 |
| 收稿时间： | 2005-11-28 |
| 修稿时间： | 2005-11-282006-04-17 |
Antimicrobe Activity of Allicin Against Ureaplasma Urealyticum in Vitro |
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| WEN Ping,GUO Yue-fang,CHEN Lei. Antimicrobe Activity of Allicin Against Ureaplasma Urealyticum in Vitro[J]. Chinese J of Dermatovenerology Integr Tradit and West Med, 2006, 5(2): 99-100 |
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| Authors: | WEN Ping GUO Yue-fang CHEN Lei |
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| Affiliation: | Central Laboratory, The Affiliated Hospital of Jiangsu University, Zhenjiang 212001, China |
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| Abstract: | Objective To examine the antimicrobe activity of allicin and 5 antibiotics against Ureaplasma urealyticum(Uu) for the guidance of rational use of antibiotics in vitro. Methods Effect of allicin and 5 antibiotics on minimun inhititory concentration(MIC) and minimum bactericidal concentration of 197 clinical isolates of Uu were detected with broth microdilution method independently. Results The effects of allicin were stronger than 5 antibiotics. MIC50 and MIC90 were 2.0 mg/L and 4.0 mg/L respectively. Conclusion Natural drug allicin has strong antimicrobe activity against Ureaplasma urealyticum in vitro. |
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| Keywords: | Ureaplasma urealyticum allicin antibiotics minimum inhibitory concentration minimum bactericidal concentration susceptibility |
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