| 老鹳草滴眼液治疗实验性家兔单纯疱疹性角膜炎的研究 |
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| 引用本文： | 张海男,贺双腾,黎杏群.老鹳草滴眼液治疗实验性家兔单纯疱疹性角膜炎的研究[J].湖南中医药大学学报,2001,21(3):27-29. |
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| 作者姓名： | 张海男 贺双腾 黎杏群 |
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| 作者单位： | 中南大学湘雅医院中西医结合研究所, |
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| 基金项目： | 湖南省中医管理局项目 ( 96 2 2 7) |
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| 摘 要： | 观察老鹳草滴眼液治疗兔实验性单纯疱疹性角膜炎的疗效。兔双眼角膜接种单纯疱疹I型病毒后，给予老鹳草滴眼液滴眼治疗，观察角膜病变，并作光镜检查角膜组织病理改变。老鹳草治疗组角膜溃疡范围较溶剂对照组明显缩小（P＜0．01）。病理形态学表明老鹳草滴眼液具有减轻角膜病理损害，保护易感细胞的作用。老鹳草滴眼液治疗兔实验性单纯疱疹性角膜炎有明显疗效。
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| 关 键 词： | 老鹳草 滴眼液 角膜炎 人疱疹病毒 组织学 光学显微镜技术 |
| 文章编号： | 1000-5633(2001)03-0027-03 |
A Study of the Treatment of Experimental HSV Keratitis With Lao guancao Eye Drops |
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| Zhang Hainan,He Shuangteng,Li Xingqun.A Study of the Treatment of Experimental HSV Keratitis With Lao guancao Eye Drops[J].Journal of Traditional Chinese Medicine University of Hunan,2001,21(3):27-29. |
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| Authors: | Zhang Hainan He Shuangteng Li Xingqun |
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| Abstract: | To observe the therapeutic effects of laoguancao eye drops on experimental HSV keratitis.Methods:After HSV I was innoculated on the cornea of rabbits,laoguancao eye drops were dripped into the rabbits'eyes.Then pathologic changes of the cornea were observed with light microscopy.Results:The cornea ulcer areas of the treatment group were smaller than those in the control group ( P <0 01).Pathological examination showed that laoguancao eye drops alleviated the cornea damage due to HSV I and protected the susceptible cornea cells.Conclusion:Topical use of laoguancao eye drops can produce marked antiviral effects on inhibiting the development of experimental herpetic keratitis in rabbits. |
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| Keywords: | Laoguancao eye drops keratitis herpes virus hominis histology light microscopy |
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