随访干预对HIV/AIDS患者社会支持及服药依从性的影响

目的 探讨随访干预对人类免疫缺陷病毒（human immune deficiency virus，HIV）感染者/艾滋病（acquired immune deficiency syndrome，AIDS）病人（简称HIV/AIDS患者）社会支持及服药依从性的效果。方法 采用分层随机抽样的方法，在随访干预前后对河南省五个艾滋病防治示范县/市的HIV/AIDS患者抗病毒治疗的社会支持度和服药依从性进行基线和随访调查评价。结果 基线和随访调查分别纳入研究对象911人和860人，其中抗病毒治疗者分别为798人和795人。HIV/AIDS患者基线与随访调查的社会支持总平均得分分别为（38.64±7.87）分和（40.36±7.45）分，差异有统计学意义（t=4.486，P<0.001）；随访干预后调查对象各维度支持得分均高于基线调查平均得分，差异均有统计学意义（均有P<0.05）。研究对象基线与随访调查抗病毒治疗服药依从性好的患者与依从性差的患者比较，差异有统计学意义（χ²=20.648，P<0.001）。结论 随访干预可以有效提高HIV/AIDS患者社会支持和服药依从性，且社会支持得分越高，服药依从性越好。

Influence of follow-up intervention on social support and medication compliance for HIV/AIDS patients

Objective To evaluate the effect of follow-up intervention on HIV/AIDS patients. Methods Stratified random sampling method was used to investigate HIV/AIDS patients from the five demonstration city in Henan Province. Baseline and follow-up survey were conducted among participants to analyze the social support and the adherence to highly active antiretroviral therapy (HAART). Results A total of 911 and 860 HIV/AIDS patients were included by the baseline and follow-up survey, among each 798 and 795 participants received HAART. The total social support scores of the baseline and follow-up survey on HIV/AIDS patients were (38.64±7.87) and (40.36±7.45), respectively, and significant differences were found (t=4.486,P<0.001). The total score of social support and its all dimensions in the following-up survey were higher than those of the baseline survey (all P<0.05). The patients adherence to HAART before and after the follow-up intervention, the significant differences were found between better medication compliance and poor medication compliance (χ2=20.648,P<0.001). Conclusions Follow-up intervention could significantly improve the social support and the adherence to HAART, and the higher social support could enhance the medication compliance.