早期低位直肠癌局部切除23例疗效分析

背景与目的:目前,早期低位直肠癌经肛门局部切除术越来越受到重视,因为它可以达到与开腹根治术类似的疗效。本研究目的是探讨早期低位直肠癌局部切除的疗效。方法:回顾性分析1989年2月～1999年4月间我院局部切除早期低位直肠癌23例的临床资料。结果:(1)12例为直肠腺癌,11例为腺瘤恶变;(2)23例中T0期17例,T1期6例;(3)有3例局部复发,其中2例再次经肛门局部扩大切除治愈,另外1例经腹会阴联合切除术;(4)本组病例术后随访均超过5年,5年生存率为95.65%。结论:只要严格掌握手术适应证,局部切除治疗早期直肠癌可取得较好的疗效,是一种切实可行的方法。

Efficacy of local resection on lower rectal cancer of early stage: efficacy of report of 23 cases

BACKGROUND & OBJECTIVE: The trans-anal local excision for lower rectal cancer of early stage may achieve the same therapeutic effect as abdominal resection. This study was to evaluate efficacy of local resection for lower rectal cancer of early stage. METHODS: Records of 23 patients with lower rectal cancer of early stage received local excision from Feb. 1989 to Apr. 1999 in our hospital were analyzed retrospectively. RESULTS: Of the 23 patients,12 were adenocarcinoma, and 11 were canceration of adenoma; 17 with tumor of stage T0, and 6 with tumor of stage T1. Three patients had local recurrence, 2 of 3 were salvaged by trans-anal local excision, and 1 of 3 was treated by abdominoperineal resection. All patients were followed-up for more than 5 years with a 5-year survival rate of 95.65%. CONCLUSION: So long as carefully considering indications of trans-anal local excision in treating patients with lower rectal cancer of early stage, good efficacy may be achieved.