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果糖二磷酸钠治疗急性脑梗死
引用本文:冉治国,刘艳玲,薛安民.果糖二磷酸钠治疗急性脑梗死[J].中国新药与临床杂志,1997(6).
作者姓名:冉治国  刘艳玲  薛安民
作者单位:洛阳市第四人民医院
摘    要:目的:观察果糖二磷酸钠(FDP)治疗急性脑梗死的疗效及不良反应。方法:将80例经CT或MRI证实的急性脑梗死病人随机分为2组。FDP组40例(男性26例,女性14例;年龄64±s17a)用FDP20g,静脉滴注qd×20d。对照组40例(男性28例,女性12例;年龄67±17a)用右旋糖酐-40葡萄糖注射液500mL加复方丹参注射液20mL,静脉滴注qd×21d。结果:FDP组总有效率为78%,对照组总有效率为53%,P<0.05。治疗期间未发现任何不良反应。结论:FDP治疗急性脑梗死是安全、有效的。

关 键 词:脑梗死  果糖二磷酸盐类  丹参  右旋糖酐类

Fructose sodium diphosphate in treatment of acute cerebral infarction
RAN Zhi-Guo,LIU Yan-Ling,XUE An-Min.Fructose sodium diphosphate in treatment of acute cerebral infarction[J].Chinese Journal of New Drugs and Clinical Remedies,1997(6).
Authors:RAN Zhi-Guo  LIU Yan-Ling  XUE An-Min
Abstract:AIM: To study the efficacy and adverse reactions of fructose sodium diphosphate (FDP) on patients with acute cerebral infarction. METHODS: The 80 acute cerebral infarction patients diagnosed by CT or MRI were divided at random into 2 groups:40 patients (M 26, F 14; age 64±s 17 a) received FDP 20 g, iv, drip, qd for 20 d. The other 40 patients (M 28, F 12; age 67±17 a) received compound Salvia miltiorrhiza 20 mL in dextran 40 glucose injection 500 mL, iv, drip, qd for 21 d. RESULTS: The total effective rates of FDP group and control gorup for acute cerebral infarction were 78% and 53%, respectively (P<0.05). No adverse effects were found. CONCLUSION: FDP is safe and useful for the treatment of acute cerebral infarction.
Keywords:cerebral infarction  fructosediphosphates  Salvia miltiorrhiza  dextrans
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