常见原发性泪腺上皮性肿瘤的组织病理学特征与复发的关系

目的分析原发性泪腺上皮性肿瘤的组织病理学特征与复发的关系,为临床诊治提供参考。方法收集128例病理诊断为原发性泪腺上皮性肿瘤患者的石蜡标本,其中最常见的三种依次为良性混合瘤74例（57．8％）,腺样囊性癌22例（17．2％）,恶性混合瘤18例（14．1％）,分析其组织病理学特征与复发的关系。结果良性混合瘤、腺样囊性癌和恶性混合瘤的复发率分别为23．0％、18．2％和27．8％,其中良性混合瘤的病理类型和包膜完整性在肿瘤的复发中具有统计学意义。结论三种常见原发性泪腺上皮性肿瘤复发率高,了解其病理表现对肿瘤的诊断、治疗方式的选择和随访时间的确定具有参考意义。

Analysis of the relationship between pathology and recurrence of primary lacrimal epithelial tumors

Objective To analyze the relationship between pathology and recurrence of primary lacrimal epithelial tumors. Methods 128 cases of primary lacrimal epithelial tumors including benign mixed tumor (74 cases, 57.8%), adenoid cystic carcinoma (22 cases, 17.2%) and malignant mixed tumor (18 cases, 14.1% ) were subjected in the study. Pathological features were analyzed and compared with their recurrence. Results The recurrent rate of benign mixed tumor, adenoid cystic carcinoma and malignant mixed tumor was 23. 0% , 18. 2% and 27. 8% , respectively. The recurrence of benign mixed tumor was statistically related to pathological classification and encapsulates. Conclusions Primary lacrimal epithelial tumors show variant types and high recurrent rate. The pathological features were decisive in diagnosis, selection of treatment and the time of follow-up.