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子痫前期患者血清及胎盘抑制素A水平变化
引用本文:刘群英,吕秀翠. 子痫前期患者血清及胎盘抑制素A水平变化[J]. 中国妇幼保健, 2010, 25(3)
作者姓名:刘群英  吕秀翠
作者单位:山东省青岛市第八人民医院产科,266100
摘    要:目的:探讨子痫前期患者血清及胎盘抑制素A的水平变化及其与病情的关系。方法:采用酶联免疫分析法检测40例子痫前期患者(子痫前期组,包括20例轻度、20例重度)、40例正常妊娠妇女(正常妊娠组)的血清抑制素A的水平;采用免疫组织化学方法检测胎盘抑制素A的水平。结果:子痫前期组患者血清、胎盘抑制素A水平[(4.82±0.13)、(497.35±6.75)μg/L]高于正常妊娠组[(1.65±0.08)、(262.34±13.35)μg/L],P0.01;重度子痫前期组患者血清、胎盘抑制素A水平较轻度子痫前期组升高(P0.01);子痫前期组患者血清、胎盘抑制素A水平与24h尿蛋白含量间呈显著正相关;重度子痫前期伴胎儿生长受限(FGR)组胎盘抑制素A水平较不伴FGR者差异无统计学意义(P0.05)。结论:子痫前期患者血清、胎盘抑制素A水平较正常妊娠妇女显著升高,且与子痫前期病情进展关系密切。

关 键 词:子痫前期  抑制素A  血清  胎盘

Changes of inhibin A levels in serum and placenta in patients with preeclampsia
LIU Qun-Ying,LV Xiu-Cui. Changes of inhibin A levels in serum and placenta in patients with preeclampsia[J]. Maternal and Child Health Care of China, 2010, 25(3)
Authors:LIU Qun-Ying  LV Xiu-Cui
Affiliation:LIU Qun-Ying,LV Xiu-Cui.Department of Obstetrics,the Eighth People's Hospital of Qingdao,Qingdao 266100,Sh,ong,China
Abstract:Objective:To explore the changes of inhibin A levels in serum and placenta in patients with preeclampsia and the relationship with degrees of preeclampsia.Methods:The serum levels of inhibin A from 40 patients with preeclampsia (preeclampsia group,20 patients with mild preeclampsia and 20 patients with severe preeclampsia) and 40 normal pregnant women (control group) were detected by enzyme-linked immunosorbent assay (ELISA),while the levels of inhibin A in placenta from preeclampsia group and control group...
Keywords:Preeclampsia  Inhibin A  Serum  Placenta  
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