| 临床分离铜绿假单胞菌的耐药性分析 |
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| 引用本文： | 朱壮春,袁强,曹蕾,郝东升. 临床分离铜绿假单胞菌的耐药性分析[J]. 上海医学检验杂志, 2005, 0(6) |
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| 作者姓名： | 朱壮春 袁强 曹蕾 郝东升 |
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| 作者单位： | 华北煤炭医学院生物科学系 河北唐山063000(朱壮春，曹蕾)，华北煤炭医学院附属医院 河北唐山063000(袁强)，华北煤炭医学院附属医院 河北唐山063000(郝东升) |
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| 摘 要： | 目的了解临床分离的铜绿假单胞菌的耐药性及变化趋势。方法对2000年~2004年分离出的1405株铜绿假单胞菌选用16种抗生素采用K irby-Bauer纸片扩散法进行药敏试验,按美国临床实验室标准化委员会(NCCLS)标准判断。结果铜绿假单胞菌最敏感的抗生素为美罗培南(总耐药率为15.3%),抗菌作用最差的抗生素为头孢曲松(总耐药率为64.1%)。铜绿假单胞菌对抗生素的耐药性呈逐年上升的变化趋势。结论加强耐药性监测,合理应用抗菌药物十分重要。
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| 关 键 词： | 铜绿假单胞菌 耐药性 抗菌药物 |
Analysis of the antibiotic resistance of clinically isolated Pseudomonas strains |
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| ZHU Zhuangchun,YUAN Qiang,CAO Lei,HAO Dongsheng. Analysis of the antibiotic resistance of clinically isolated Pseudomonas strains[J]. Shanghai Journal of Medical Laboratory Sciences, 2005, 0(6) |
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| Authors: | ZHU Zhuangchun YUAN Qiang CAO Lei HAO Dongsheng |
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| Affiliation: | ZHU Zhuangchun,YUAN Qiang,CAO Lei,HAO Dongsheng. Department of Biological Sciences,North China Coal Medical College,Hebei Tangshan 063000,China |
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| Abstract: | Objective To explore the antibiotic resistance and its changing trend of Pseudomonas aeruginosa(P.aeruginosa). Methods Drug-resistance test with 16 kinds of common antibiotics of 1 405 strains of P.aeruginosa was performed by Kirby-Bauer method.The drug sensitive experiment was based on the standard of the National Committee for Clinical Laboratory Standards(NCCLS) from 2000 to 2004. Results Meropenem was of the strongest activity against P.aeruginosa with the total drug-resistance rate of 15.3%,ceftriaxone was of the weakest with the total drug-resistance of 64.1%.The drug-resistance rate of PA was increasing year by year. Conclusions It is very important to select antibiotics correctly according to the results of susceptibility tests. |
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| Keywords: | Pseudomonas aeruginosa Resistance Antibiotic |
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