Maternal cytoglobin (CYGB) serum levels in normal and preeclamptic pregnancies |
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Authors: | Ahter Tanay Tayyar Ahmet Tayyar Sukran Kozali Resul Karakus Seren Karakus Ilkbal Temel Yuksel |
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Affiliation: | 1. Department of Obstetrics and Gynecology, Health Sciences University, Zeynep Kamil Maternity and Children’s Training and Research Hospital, ?stanbul, Turkey;2. drahtertayyar@yahoo.com;4. Department of Obstetrics and Gynecology, Health Sciences University, Kanuni Sultan Süleyman Education and Research Hospital, Istanbul, Turkey |
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Abstract: | Objective: To investigate cytoglobin levels in women with preeclampsia and women with uncomplicated pregnancies.Materials and methods: A cross-sectional study including 26 pregnant women complicated with early-onset preeclampsia (EO-PE) and 26 pregnant women complicated with late-onset preeclampsia (LO-PE) were recruited for the study group. Twenty-seven healthy pregnant women selected randomly were included in the control group. The serum CYGB concentrations were measured using an enzyme-linked immunosorbent assay.Results: Gestational age at delivery and mean birth weight were significantly lower in the preeclampsia groups than in the control group and were found to be the lowest in the EO-PE group (p?.001). Serum CYGB levels were significantly higher in the EO-PE and LO-PE groups as compared with the control group (9.99 (6.08) ng/ml (EOPE), 10.04 (7.04) ng/ml (LOPE) versus 2.84 (0.82) ng/ml), (p?.001). However, a significant difference was not found between the EO-PE and LO-PE groups regarding CYGB levels (p?=?1.000).Conclusions: Serum CYGB levels were significantly higher in patients with EO-PE and LO-PE as compared to healthy pregnant women. |
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Keywords: | Cytoglobin early-onset preeclampsia late-onset preeclampsia oxidative stress treatment |
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