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Maternal cytoglobin (CYGB) serum levels in normal and preeclamptic pregnancies
Authors:Ahter Tanay Tayyar  Ahmet Tayyar  Sukran Kozali  Resul Karakus  Seren Karakus  Ilkbal Temel Yuksel
Institution:1. Department of Obstetrics and Gynecology, Health Sciences University, Zeynep Kamil Maternity and Children’s Training and Research Hospital, ?stanbul, Turkey;2. drahtertayyar@yahoo.com;4. Department of Obstetrics and Gynecology, Health Sciences University, Kanuni Sultan Süleyman Education and Research Hospital, Istanbul, Turkey
Abstract:Objective: To investigate cytoglobin levels in women with preeclampsia and women with uncomplicated pregnancies.

Materials and methods: A cross-sectional study including 26 pregnant women complicated with early-onset preeclampsia (EO-PE) and 26 pregnant women complicated with late-onset preeclampsia (LO-PE) were recruited for the study group. Twenty-seven healthy pregnant women selected randomly were included in the control group. The serum CYGB concentrations were measured using an enzyme-linked immunosorbent assay.

Results: Gestational age at delivery and mean birth weight were significantly lower in the preeclampsia groups than in the control group and were found to be the lowest in the EO-PE group (p?p?p?=?1.000).

Conclusions: Serum CYGB levels were significantly higher in patients with EO-PE and LO-PE as compared to healthy pregnant women.
Keywords:Cytoglobin  early-onset preeclampsia  late-onset preeclampsia  oxidative stress  treatment
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