Significance of assay of nucleated RBCs in umbilical cord blood in neonates with meconium-stained amniotic fluid |
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| Authors: | M Elsokkary A Mamdouh W Nossair O Abd El Fattah H Hemeda S Sallam |
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| Institution: | 1. Department of Obstetrics and Gynecology, Ain Shams University, Cairo, Egypt;2. Department of Obstetrics and Gynecology, Faculty of Medicine, Zagazig University, Cairo, Egypt;3. Department of Reproductive Health Research, National Research Centre, Cairo, Egypt;4. Department of Obstetrics and Gynecology, Al-Arish Hospital, Cairo, Egypt |
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| Abstract: | Background: Approximately 8–15% of all infants are born with evidence of meconium-stained amniotic fluid (MSAF). MSAF is a potentially serious sign of fetal compromise and may indicate fetal hypoxiaObjectives and aim of the work: The present study was designed to evaluate the relationship between meconium stained amniotic fluid and fetal nucleated red blood cell counts. As well, we aim to evaluate the relationship between the presence of meconium in amniotic fluid and Apgar scores in neonates.Subjects and methods: A prospectively case-controlled study was performed on 40 women with clear amniotic fluid as control and 40 women with meconium-stained amniotic fluid as the study group. At delivery, 2?ml of umbilical cord blood was collected and analyzed for nucleated red blood cell (NRBC).Results: The mean NRBC counts in meconium-stained amniotic fluid was significantly higher than the control group (18.35?±?7.7 and 9.6?±?4.96), respectively (p?p?Conclusion: Our results support previous studies which indicate the presence of meconium can be associated with chronic fetal hypoxia as demonstrated by elevated fetal NRBC levels. |
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| Keywords: | Meconium-stained amniotic fluid nucleated RBCS umbilical cord blood |
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