| 高效液相色谱法测定盐酸噻氯匹定胶囊的含量 |
| |
| 引用本文： | 陈民辉,贾立革.高效液相色谱法测定盐酸噻氯匹定胶囊的含量[J].中国生化药物杂志,2004,25(1):26-27. |
| |
| 作者姓名： | 陈民辉 贾立革 |
| |
| 作者单位： | 1. 江苏省药品检验所,江苏,南京,210008
2. 北京军医学院,北京,100071 |
| |
| 摘 要： | 目的建立盐酸噻氯匹定胶囊的高效液相色谱 (HPLC)含量测定方法。方法盐酸噻氯匹定胶囊的HPLC含量测定色谱条件 :ODS柱 ,流动相 :0 .1%三乙胺溶液 (用磷酸调pH 2 .5 ) 甲醇 (6 0∶4 0 ) ,检测波长 :2 33nm ,流速 :1.0ml/min。结果盐酸噻氯匹定胶囊HPLC含量测定方法的线性范围为 10ng～ 10 μg ,日内RSD为0 .5 0 % ,日间RSD为 0 .4 6 %。结论此方法简便 ,准确可靠 ,耐用性好
|
| 关 键 词： | 盐酸噻氯匹定 高效液相色谱法 含量测定 |
| 文章编号： | 1005-1678(2004)01-0026-02 |
| 修稿时间： | 2003年12月2日 |
Quantitative determination of Ticlopidine hydrochloride capsules by high performance liquid chromatography |
| |
| CHEN Min-hui,JIA Li-ge.Quantitative determination of Ticlopidine hydrochloride capsules by high performance liquid chromatography[J].Chinese Journal of Biochemical Pharmaceutics,2004,25(1):26-27. |
| |
| Authors: | CHEN Min-hui JIA Li-ge |
| |
| Abstract: | PurposeA high performance liquid chromatography(HPLC) method for quantitative determination of Ticlopidine hydrochloride capsules had been developed.MethodsThe HPLC method for determination of Ticlopidine hydrochloride capsules was:ODS column,mobile phase:0.1% tyiethylamine(adjusted to pH 2.5 with 85% phosphoric acid)-methanol(60∶40),detector wavelength:233 nm,flow rate:1.0 ml/min.ResultsThe linear range was 10 ng～10 μg,quantitation limit was 10 ng,and RSD within day was 0.50%,RSD between days was 0.46%.ConclusionThe method was simple and reliable. |
| |
| Keywords: | Ticlopidine hydrochloride high performance liquid chromatography quantitative determination |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
