CT对侵袭性肺真菌感染的诊断价值

目的 分析侵袭性肺真菌感染的CT表现,并评价CT导引下穿刺的应用价值.方法 回顾性分析北京卫生部中日友好医院2000至2008年17例经CT导引下穿刺病理诊断为侵袭性肺真菌感染患者的CT表现,观察病变的形态、范围、边界、密度和病灶大小特点,并分析其与病原菌的关系.结果 ①17例侵袭性肺真菌感染中白色念珠菌7例,新型隐球菌5例,曲霉菌5例.②本组病例中肺叶、段实变型6例,斑片及小结节型4例,肿块型7例.③纤维支气管镜钳检及灌洗阳性率为35.3%(6/17).④CT导引下穿刺主要并发症为气胸11.8%(2/17),均未做特殊处理而自愈.结论 真菌性肺炎影像学表现缺乏特异性,CT导引下穿刺可与纤维支气管镜检查互补,较好的实现了早期微创条件下病原学诊断.

Abstract：

Objective To analyze the computed tomographic (CT) features of invasive pulmonary fungal infections ( IPFI ) and evaluate the value of CT-guided percutaneous biopsy. Methods Seventeen IPFI cases diagnosed by CT-guided percutaneous biopsy were recruited. The distribution, extent, density and size of IPFI were analyzed in correlation with the final diagnosis retrospectively. And the relationship with the causative factor of mycosis was also assessed. Results ① Candida albicans (n = 7 ) and cryptococcosis & aspergillus (n = 5 ) were identified. ② It showed segmental on lobar consolidation within lung field (n =6), mixture of patterns and nodule (n =4) and mass (n =7). ③The overall diagnostic accuracy of fiberoptic bronchoscopy examination was 35. 3％. ④The incidence of complicated pneumothorax was 11.8％ (2/17). These cases were self-limited without any special treatment. Conclusion The CT findings of PFI are too complex to be easily distinguished from other diseases. And the CT-guided percutaneous is a safe and effective procedure.

Diagnostic value of computed tomography in invasive pulmonary fungal infections

Objective To analyze the computed tomographic (CT) features of invasive pulmonary fungal infections ( IPFI ) and evaluate the value of CT-guided percutaneous biopsy. Methods Seventeen IPFI cases diagnosed by CT-guided percutaneous biopsy were recruited. The distribution, extent, density and size of IPFI were analyzed in correlation with the final diagnosis retrospectively. And the relationship with the causative factor of mycosis was also assessed. Results ① Candida albicans (n = 7 ) and cryptococcosis & aspergillus (n = 5 ) were identified. ② It showed segmental on lobar consolidation within lung field (n =6), mixture of patterns and nodule (n =4) and mass (n =7). ③The overall diagnostic accuracy of fiberoptic bronchoscopy examination was 35. 3％. ④The incidence of complicated pneumothorax was 11.8％ (2/17). These cases were self-limited without any special treatment. Conclusion The CT findings of PFI are too complex to be easily distinguished from other diseases. And the CT-guided percutaneous is a safe and effective procedure.