支气管动脉栓塞联合垂体后叶素治疗大咯血疗效观察

目的：探讨大咯血患者在行支气管动脉栓塞（r3AE）后联合应用垂体后叶素是否可以提高止血效果。方法：回顾性分析34例大咯血患者的临床资料。根据BAE后是否联合应用垂体后叶素分为联合组和对照组。①联合组：在BAE后将垂体后叶素按0．1U／kg／h剂量持续静脉滴注或静脉泵入。②对照组：BAE后不再应用垂体后叶素及其它止血药物。观察两组患者控制出血的有效率和不良反应。结果：①联合组DSA有12例（63．2％）可见明确的对比剂外溢；全部患者可以见到病变侧支气管动脉增粗扩张，走形迂曲，杂乱；有7例为双侧出血，其余12例为单侧病变。对照组8例（53．3％）有对比剂外溢表现；有5例为双侧病变，另10例为单侧病变。②联合组控稍出血的总有效率89．47％，对照组总有效率为60．0％，联合组总有效率显著优于对照组（P〈0．05）。礓）联合组不良反应的发生率高于对照组，但通过对症处理和停药后症状消失。结论：在BAE的基础上联合应用小剂量的垂体后叶素显著减少了再出血风险，提高了BAE的成功率。

The Efficacy Evaluation of Bronchial Artery Embolization Combined with Pituitrin in the Treatment of Massive Hemoptysis

Objective：To investigate efficacy of bronchial artery embolization combined with Pituitrin m the treat- The total efficiency was 89.47% in Combined group and 60% in Control group. There was significantly difference （P〈O.05）, also, the side effect is higher in Combined group, but it was mild and controllable. Conclusion.the application of small dose Pituitrin combined with BAE may obviously improve the efficiency and reduce the risk of rebleeding.