脑血管疾病中血清HCY和血脂检测结果相关性分析

目的：探讨脑血管疾病患者血清同型半胱氨酸（HCY）和血脂中各指标的含量与脑血管疾病发生的相关性。方法：检测66例脑血管患者和56例非脑血管疾病对照组人群血清同型半胱氨酸（HcY）、总胆固醇frC）、甘油三（TG）、低密度脂蛋白胆固醇（LDL—c）及高密度脂蛋白胆固醇（HDL—c）水平。结果：脑血管疾病患者血清HCY、TG、TCHO、LDL—c含量分别为（16．11±9．19）μmol／L、（1．26±0．40）mmol／L、（4．61±0．83）mmol／L、（3．20±0．75）mmol／L，而非脑血管疾病患者血清中其相应含量分别为（11．70±4．75）μmol／L、（1．02±0．34）mmol／L、（3．93±O．82）mmol／L、（2．64±0．70）mmol／L，各指标在两组血清中含量具有显著性差异（P〈0．05）；而HDL—C两组比较差异无统计学意义（P〉O．05）。结论：血清中HCY和TCHO、TG血脂指标水平与脑血管疾病两者有关联，可以作为相关危险因素为脑血管疾病进行研究和治疗提供参考依据。

Correlation Study of HCY and Blood Lipid Biomarkers in Cerebrovascular Disease

Objective：Detect the levels of HCY and blood lipid biomarkers in patients with cerebrovascular dis- ease, and explore the correlation between their levels and the occurrence of cerebrovascular disease. Methods：Bio- chemical analyzer known as XL-300 was applied to detect serum levels of HCY, TG, TC, LDL-C, and HDL-C in both cerebrovascular disease group and control group parallelly. Results：Levels of HCY, TG, TCHO, LDL-C in serum of cerebrovaseular disease were （16.11 ±9.19 μmol/L）, （1.26 ±0.40 mmol/L）, （4.61 ± 0.83 mmol/L）, （3.20 ± 0.75 mmol/L）, while their corresponding contents in serum of control group were （11.70 ± 4.75 μmol/L）,（1.02 ± 0.34 mmol/L）, （3.93 ± 0.82mmol/L）, and （2.64 ± 0.70 mmol/L）. The indexes in the two groups have significant difference in serum con- tent （P〈0.05）. However, levels of HDL-C in the two groups no significant difference was discovered （P 〉0.05）. Conclu- sion：Between the levels of HCY and TG, TCHO, LDL-C in the serum and cerebrovascular disease were associated, which can be considered as risk factors servng as reference for the study of cerebrovascular disease and treatment.