还原型谷胱甘肽治疗药物性肝炎中的疗效观察

目的：探讨还原型谷胱甘肽在药物性肝炎中的应用及其疗效观察。方法：将某医院感染科收治诊断明确的药物性肝炎病人80例随机分成治疗组40例和对照组40例，治疗组给予5％葡萄糖注射液250m1＋还原型谷胱甘肽1．2g静脉滴注，每天一次，疗程2周；对照组给予5％葡萄糖注射液250m1＋门冬氨酸钾镁注射液20ml静脉滴注，每天一次，疗程2周，观察治疗前后两组肝功能、临床症状、体征的变化情况。结果：治疗组总有效率97．5％，对照组总有效率67．5％。治疗组肝功能、临床症状、体征改善明显优于对照组（p〈0．05）。结论：还原型谷胱甘肽在药物性肝炎的治疗中有着良好的疗效。

The observation of clinical curative effect of drug-induced hepatitis cured by reduced glutathione

Objective：To discuss the application of drug-induced hepatitis cured by reduced glutathione and the observation of clinical curative effect of it.Methods：The toatal of 80 cases of drug-induced hepatitis which were deft- nite diagnosed by our hospital infection branch were randomly divided into the treatment group with 40 cases and the control group with 40 cases,the treatment group based on this give 5% glucose injection＋ reduced glutathione 1.2g,qd, the course of treatment is two weeks.And the control group with 40 cases were given 5% glucose injection＋nmda potassium magnesium injection 20ml,qd, the course of treatment is two weeks.To observe the liver function,the clinical symptoms and signs before and ＂after treatment.Results：The effective rate of the treatment group was 97.5%;the effec- tive rate of the control group was 67.5%.The improvement of the liver function,the clinical symptoms and signs in the treatment group were much better than that in the control group P〈O.OS.Conclusion： Reduced glutathione has very good efficacy in treating drug-induced hepatitis.