| 复元活血汤抗炎镇痛作用的实验研究 |
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| 引用本文： | 祖丽红,王继文.复元活血汤抗炎镇痛作用的实验研究[J].中医正骨,2003,15(9):17-18. |
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| 作者姓名： | 祖丽红 王继文 |
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| 作者单位： | 河南省郑州市中医医院,450007 |
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| 摘 要： | 为研究复元活血汤的抗炎、镇痛作用，进行了药效学研究。结果显示，复元活血汤对醋酸引起的小鼠腹腔毛细血管通透性增加、角叉菜胶所致的大鼠足跖肿胀、二甲苯所致的小鼠耳肿胀均有显著的抑制作用；能显著降低小鼠腹腔注射醋酸引起的扭体反应次数，明显提高小鼠热板法的痛阈值，说明该药有较强的抗炎、镇痛作用。
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| 关 键 词： | 复元活血汤 药效学 抗炎 镇痛 药物作用 动物实验研究 大鼠 小鼠 |
| 文章编号： | 1001-6015(2003)09-0017-02 |
| 修稿时间： | 2003年2月12日 |
AN EXPERIMENTSL STUDY ON THE EFFECT OF “FUYUAN HUOXUE TANG”ON ANTI-INFLAMMATION AND ANALGESIA |
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| Zu Lihong and Wang Jiwen TCM Hospital of Zhengzhou City,Zhengzhou.AN EXPERIMENTSL STUDY ON THE EFFECT OF “FUYUAN HUOXUE TANG”ON ANTI-INFLAMMATION AND ANALGESIA[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2003,15(9):17-18. |
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| Authors: | Zu Lihong and Wang Jiwen TCM Hospital of Zhengzhou City Zhengzhou |
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| Institution: | Zu Lihong and Wang Jiwen TCM Hospital of Zhengzhou City,Zhengzhou 450007 |
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| Abstract: | The anti-inflammatory and analgesic effect of "FUYUAN HUOXUE TANG""(FHT, a TCD decoction for restoring the vital energy and activating the blood circulation) was explored through pharmacodynamics studies. The results showed that FHT could significantly inhibit the acetic-acid-induced increase of mouse abdominal capillary permeability, carrageenin-induced rat planta edema and xylol-induced mouse ear edema, reduce the times of acetic-acid-induced mouse body twisting and improve the pain threshold of mouse hot plate method, suggesting that the drug has a strong anti-inflammatory and analgesic effect. |
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| Keywords: | FUYUAN HUOXUE TANG"/pharmacodynamics anti-inflammation/drug action analgesia/drug action experimental study animal mouse rat |
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