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恶性肿瘤患者多重耐药菌感染危险因素的研究进展
引用本文:韩建庚,路佳,张洁. 恶性肿瘤患者多重耐药菌感染危险因素的研究进展[J]. 现代药物与临床, 2021, 36(7): 1541-1544
作者姓名:韩建庚  路佳  张洁
作者单位:天津医科大学肿瘤医院 药学部 国家肿瘤临床医学研究中心 天津市肿瘤防治重点实验室 天津市恶性肿瘤临床医学研究中心,天津 300060;天津医科大学肿瘤医院 感染管理科 国家肿瘤临床医学研究中心 天津市肿瘤防治重点实验室 天津市恶性肿瘤临床医学研究中心,天津 300060
基金项目:天津市科技重大专项与工程(18ZXXYSY00120,18ZXXYSY00020)
摘    要:我国恶性肿瘤发病人数居全球第一,而感染是恶性肿瘤常见的并发症,严重影响恶性肿瘤患者的疗效,延长住院时间,增加治疗费用,成为恶性肿瘤患者死亡的重要原因.近年来,随着抗菌药物的广泛应用,恶性肿瘤患者发生多重耐药菌感染比率逐年升高,对患者造成极大危害.因此提升对恶性肿瘤患者发生多重耐药菌感染的危险因素的认识至关重要,故对恶性...

关 键 词:恶性肿瘤患者  多重耐药菌  感染  危险因素
收稿时间:2020-12-25

Research progress on risk factors of multidrug-resistant bacteria infection in patients with malignant tumor
HAN Jian-geng,LU Ji,ZHANG Jie. Research progress on risk factors of multidrug-resistant bacteria infection in patients with malignant tumor[J]. Drugs & Clinic, 2021, 36(7): 1541-1544
Authors:HAN Jian-geng  LU Ji  ZHANG Jie
Affiliation:College of Pharmacy, Hebei College of Traditional Chinese Medicine, Shijiazhuang 050091, China;Tianjin Key Laboratory of Safety Evaluation Enterprise of Traditional Chinese Medicine Injections, Tianjin 300410, China;Tianjin Tasly Pride Pharmaceutical Co., Ltd., Tianjin 300410, China;Tianjin Key Laboratory of Safety Evaluation Enterprise of Traditional Chinese Medicine Injections, Tianjin 300410, China
Abstract:The number of cancer patients in China ranks first in the world, and infection is a common complication of cancer, which seriously affects the treatment effect of cancer patients. Prolonging hospital stay and increasing treatment costs have become an important cause of death of cancer patients. In recent years, with the wide application of antibiotics, the infection rate of multidrug resistant organisms (MDRO) in patients with malignant tumor is increasing year by year, which causes great harm to patients. Therefore, it is very important to improve the understanding of the risk factors of MDRO infection in patients with malignant tumor, so this paper reviews the risk factors of MDRO infection in patients with malignant tumor, in order to provide reference for clinical prevention of MDRO infection.
Keywords:active ingredients of traditional chinese medicine  molecular docking  high-throughput screening  and cell membrane chromatography
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