肝硬化自发性细菌性腹膜炎的影响因素分析

目的探讨肝硬化自发性细菌性腹膜炎（SBP）与其相关影响因素的关系。方法在276例肝硬化患者中，对SBP的发生率与其相关影响因素SBP病史、腹水总蛋白、消化道出血、Child-Pugh分级、血清白蛋白、总胆红素、胃镜检查及腹腔穿刺术的关系进行研究。结果既往有或者无SBP病史，其SBP的发生率分别为73．5％和23．1％；腹水总蛋白≤10g／L或者〉10g／L，其SBP的发生率分别为44．4％和8．6％（P〈0．05）；Child-PughC级或者A、B级，其SBP的发生率分别为41．0％和20．1％；有或者无消化道出血，其SBP的发生率分别为37．4％和23．6％；血清白蛋白≤28g／L或者〉28g／L，其SBP的发生率分别为35．7％和22．6％。结论肝硬化SBP发生率与SBP病史、腹水总蛋白≤10g／L、消化道出血、Child-PughC级、血清白蛋白≤28g／L有明显的相关性，而与胃镜检查和腹腔穿刺无明显相关性。

Influencing factors in spontaneous bacterial peritonitis patients with hepatic cirrhosis

Objective To study the relationship between spontaneous bacterial peritonitis （SBP） with hepatic cirrhosis and its influencing factors. Methods 276 patients with confirmed hepatic cirrhosis were investigated with the incidence of SBP and its influencing factors the history of SBP, number of ascitic fluid total protein, digestive tract hemorrhage, Child-Pugh grades, number of serum albumin, number of serum total bilirubin, gastroseopy and abdominal para- centesis. Results The incidences of SBP of patients with or without history of SBP were 73.5~ and 23. 1 % （P〈0. 05）, respectively. The incidences of SBP of patients with ascitic fluid total protein 410 g/L and 〉10 g/L were 44. 4% and 8.6% （PG0. 05）, respectively. The incidences of SBP of patients of Child-Pugh C and A-B were 41.0% and 20. 1%（P 〈0. 05）, respectively. The incidences of SBP of patients of digestive tract hemorrhage or not were 37.4% and 23.6% （P 〈0. 05）. Conclusion The incidences of SBP is related to the history of SBP, ascitie fluid total protein, digestive tract hemorrhage, Child-PughC, serum albumin.