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Long-term risk of hypertension and chronic kidney disease in living kidney donors |
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| Authors: | Kim S H Hwang H S Yoon H E Kim Y K Choi B S Moon I S Kim J C Hwang T K Kim Y S Yang C W |
| Affiliation: | a Department of Internal Medicine, Chung-Ang University, Seoul, Korea b Department of Internal Medicine, Catholic University of Korea, Seoul, Korea c Catholic Transplantation Research Center, Catholic University of Korea, Seoul, Korea d Department of Surgery, Catholic University of Korea, Seoul, Korea e Department of Urology, Catholic University of Korea, Seoul, Korea |
| Abstract: | ObjectiveThe aim of this study was to assess the long-term risks of chronic kidney disease and arterial hypertension in living kidney donors.MethodsDonors who were followed for more than 1 year after nephrectomy were included. We assessed each donor's blood pressure, urine protein, and estimated glomerular filtration rate (eGFR).ResultsThe follow-up rate was 11% (154 out of 1,356 donors), only 19% of whom were followed by nephrologists. Blood pressure had increased from 113/75 to 116/77 mm Hg (P < .01), urinary protein excretion after donation did not increase, and renal function was well preserved after donor nephrectomy. However, 33 patients (21.4%) showed a decreased eGFR of <60 mL/min/1.73 m2, and 3 donors developed end-stage renal disease that required renal replacement therapy.ConclusionsThe follow-up rate of living donors after donation was low, and we observed an increased risk of developing chronic kidney disease after donation. |
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