Acute myopericarditis with pulmonary infiltration and hypereosinophilia

A 31 year-old male had the sudden onset of left ventricular failure, left ventricular apical thrombus, large pericardial effusion, pulmonary infiltrates and up to 59% eosinophils in the differential leucocyte count. A pericardial biopsy showed eosinophilic infiltration. The whole clinical picture improved dramatically with corticosteroid therapy. After 1 year of treatment with prednisone left ventricular function improved markedly, pericardial effusion disappeared, eosinophils were absent on the peripheral blood smear and the patient was asymptomatic. No endocardial thickening was detected by echocardiography.