Ovine scrapie: Follow-up of sheep belonging to an endemic scrapie-infected flock |
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Authors: | J. Chatelain C. Dautheville-guibal |
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Affiliation: | (1) Formation de Recherche Associée C. Bernard Neurochilnie des Communications Cellulaires, Hôpital St Louis, 1 Avenue C. Vellefaux, 75475, 10 Paris Cedex, France;(2) Laboratoire de Biologie Cellulaire et d Immunologie, Faculté de Mécine, Avenue Kennedy, 30000 Nimes, France |
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Abstract: | There is a close similarity between the unconventional virus-induced ovine scrapie and human Creutzfeldt-Jakob disease. Since infection might be transmitted orally, the ovine production of an endemically scrapie-infected farm was studied. About 80% of the annual production are sold (50% as butcher-meat, 30% as breeding animals), and scrapie appears in 20% of the sheep kept on the farm. Was the same proportion of butcher-meat animals scrapie-infected? Since the scrapie agent has been detected in “clinically normal” lambs, the same problem occurs with breeding-sheep and “apparently healthy” animals: are they carriers of the pathogenic agent? Are they responsible for the spread of the ovine disease and/or of the human disease? |
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Keywords: | Scrapie Creutzfeldt-Jakob disease Ovine meat consumption Illness spread |
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